The Council to Improve Foodborne Outbreak Response (CIFOR) is pleased to announce the release of the Outbreaks of Undetermined Etiology (OUE) Guidelines. The OUE Guidelines are designed to provide recommendations on “universal” collection, shipment, testing, and retention of foodborne outbreak specimens in the event that an etiology is elusive, even in the early stages of an investigation. They cover both infectious and non-infectious agents, and are primarily intended to inform health departments at the state and local levels, in making recommendations on specimen collection for foodborne outbreaks. A companion OUE Agent List provides detailed information on infectious and non-infectious agents that can be responsible for foodborne illness. These guidelines are available on the CIFOR website and can be accessed as a FileMaker Go iOS application or a runtime Windows version for PC. For more information please contact Kirsten Larson.